IDENTIFICATION OF RESIDUES OF SARS-COV NSP1 THAT DIFFERENTIALLY AFFECT INHIBITION OF GENE EXPRESSION AND ANTIVIRAL SIGNALING.

Identification of residues of SARS-CoV nsp1 that differentially affect inhibition of gene expression and antiviral signaling.

An epidemic of halloween cookie card Severe Acute Respiratory Syndrome (SARS) led to the identification of an associated coronavirus, SARS-CoV.This virus evades the host innate immune response in part through the expression of its non-structural protein (nsp) 1, which inhibits both host gene expression and virus- and interferon (IFN)-dependent sign

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Amundsen Sea Embayment ice-sheet mass-loss predictions to 2050 calibrated using observations of velocity and elevation change

Mass loss from the Amundsen Sea Embayment of the West Antarctic Ice Sheet is a major contributor to global sea-level rise (SLR) and has been increasing over recent decades.Predictions of future SLR are increasingly modelled using ensembles of simulations within which model parameters and external forcings are varied within credible ranges.Accuratel

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